Future Global Outlook in Gastrointestinal and Liver Disorders: Consensus and Perspectives from the Leaders of Member Societies of the World Gastroenterology Organization

Abstract

Background and Aims: Gastrointestinal (GI) and liver diseases are common and remain major contributors to global morbidity and mortality, with disease patterns increasingly shifting toward metabolic and functional etiologies. Anticipating these evolving challenges, the World Gastroenterology Organization (WGO), comprising 121 national and regional societies, undertook a global initiative to identify key GI and liver health areas across its member countries over the next five years (2025-2030).

Methods: A 77-item structured questionnaire was developed by the WGO Clinical Research Committee, encompassing four core domains: general priorities, research, patient care, and education/teaching. The survey was pilot-tested and refined before online dissemination to leaders of WGO-affiliated GI societies. Responses were collected anonymously and rated using a 5-point Likert scale. Consensus levels were defined a priori and categorized as strong, moderate, modest, or no consensus.

Results: Thirty-one GI leaders from 25 countries completed the survey. Consensus was achieved in nearly 60% of statements. Fatty liver disease was the only item that reached a strong consensus. Research domains had the highest agreement (78.6%), followed by general issues (58.3%), patient care (52.6%), and education/teaching (50%). Key areas of moderate consensus included the need for guideline implementation, public education, and expanded research opportunities. Barriers included insufficient funding, limited government support, and inconsistent access to training resources.

Conclusions: This global consensus highlights priority areas and barriers in GI and liver health for the next five years. Addressing metabolic liver disease, strengthening research infrastructure, enhancing endoscopic standards, and improving education will require coordinated international policy, funding, and capacity-building efforts.