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Affiliations
Quan-Yao Ban
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Hua-Shan Li
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Xue-Xue Jiang
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Mei Liu
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Xin-Yao Ge
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Mu-Jiao Lu
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Shi-Ying Guo
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Ying Chen
Department of Gastroenterology, The Affiliated Wuxi Children’s Hospital of Jiangnan University, Wuxi, Jiangsu, China
Qiong Lin
Department of Gastroenterology, The Affiliated Wuxi Children’s Hospital of Jiangnan University, Wuxi, Jiangsu, China
Hong Xu
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Wei-Qi He
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Ning Ding
Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China
Juan-Min Zha
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
How to Cite
Current Applications of Colorectal Cancer Organoids: A Review
- Quan-Yao Ban ,
- Hua-Shan Li ,
- Xue-Xue Jiang ,
- Mei Liu ,
- Xin-Yao Ge ,
- Mu-Jiao Lu ,
- Shi-Ying Guo ,
- Ying Chen ,
- Qiong Lin ,
- Hong Xu ,
- Wei-Qi He ,
- Ning Ding ,
- Juan-Min Zha
Abstract
Colorectal cancer is a prevalent malignancy, with advanced and metastatic forms exhibiting poor treatment outcomes and high relapse rates. To enhance patient outcomes, a comprehensive understanding of the pathophysiological processes and the development of targeted therapies are imperative. The high heterogeneity of colorectal cancer demands precise and personalized treatment strategies. Colorectal cancer organoids, a three-dimensional in vitro model, have emerged as a valuable tool for replicating tumor biology and exhibit promise in scientific research, disease modeling, drug screening, and personalized medicine. In this review, we present an overview of colorectal cancer organoids and explore their applications in research and personalized medicine, while also discussing potential future developments in this field.