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Affiliations
Ana Maria Garcia-Cabrera
Virgen del Rocío University Hospital, Seville, Spain
Fernando de la Portilla
Virgen del Rocío University Hospital, Seville, Spain
Rosa María Jiménez-Rodríguez
Virgen del Rocío University Hospital, Seville, Spain
Jorge Manuel Vázquez –Monchul
Virgen del Rocío University Hospital, Seville, Spain
María Luisa Reyes- Díaz
Virgen del Rocío University Hospital, Seville, Spain
Irene María Ramallo -Solís
Virgen del Rocío University Hospital, Seville, Spain
José Pintor-Tortolero
Virgen del Rocío University Hospital, Seville, Spain
Sandra Dios-Barbeito
Virgen del Rocío University Hospital, Seville, Spain
Francisco Javier Padillo- Ruiz
Virgen del Rocío University Hospital, Seville, Spain
How to Cite
Efficacy of Sacral Nerve Stimulation in Non-constipated Irritable Bowel Syndrome Patients: A Systematic Review
Abstract
Background and Aims: Irritable bowel syndrome (IBS) is a prevalent disorder with a complex and heterogeneous physiopathology, including a dysregulation of gut-brain axis. Treatment for IBS is targeted to the predominant symptom and requires a multidisciplinary approach. This review aims to evaluate the efficacy and safety of sacral nerve stimulation in non-constipated IBS patients
Methods: A literature search was carried out on MEDLINE, The Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science databases for all relevant articles. Quality of included papers was assessed using standardized guidelines
Results: Of 129 initial citations, 7 articles met our predefined inclusion criteria, including five randomized trials, a pilot study and a descriptive follow-up study. Five of 7 studies reported a positive effect of sacral nerve stimulation on symptoms and quality of life improvement in non-constipated IBS patients. No study reported serious adverse events.
Conclusions: Despite initial promising results of sacral nerve stimulation in non-constipated IBS patients, studies with larger sample sizes and longer follow-up are required.