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Affiliations
Yuichi Sanada
Department of Surgery, Saiseikai Kure Hospital; Department of Surgical Oncology, Research Institution for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
Kazuhiro Yoshida
Department of Surgical Oncology, Research Institution for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
How to Cite
A Case of Benign Intraductal Papillary Mucinous Neoplasm of the Pancreas Containing Two Major Subtypes
Abstract
Here we report a case of benign intraductal papillary-mucinous neoplasm (IPMN) of the pancreas containing two major subtypes. A 73-year-old man underwent pancreatoduodenectomy for a cystic mass, 5.0 cm in diameter. Histopathologic examinations revealed that IPMN was composed of gastric-type adenoma and intestinal-type borderline lesion. Marked intraluminal nodular growth was observed in the center of the tumor composed of intestinal-type cells positive for MUC2. Our observations suggest that gastric-type epithelium is a precursor of intestinal-type lesions in the stepwise progression of IPMN.