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Affiliations
Simona Rednic
Department of Rheumatology, University of Medicine and Pharmacy, Cluj-Napoca, Romania
Claudiu Marinescu
Department of Rheumatology, University of Medicine and Pharmacy, Cluj-Napoca, Romania
Romeo Chira
Department of Endoscopy – 1st Medical Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania
Liliana Rogojan
Department of Pathology, University of Medicine and Pharmacy, Cluj-Napoca, Romania
Nicolae Rednic
4th Medical Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania
How to Cite
Treatment with Infliximab in a Patient with Ankylosing Spondylitis and Crohn’s Disease
Vol 15 No 4: December 2006
Section: Case Reports
Pages: 379-382
Abstract
The association of Crohn's disease and ankylosing spondylitis is described in up to 30% of cases. Treatment of both conditions is not an easy task. We present the case of a 53 year old woman, diagnosed with colonic Crohn's disease and ankylosing spondilitis, treated initially with increasing doses of sulphasalazine and moderate dose of corticosteroids, with the persistence of severe gastrointestinal and articular symptoms. She underwent therapy with tumor necrosis factor alpha (TNFalpha) inhibitor Infliximab, with a spectacular improvement of symptoms, signs and quality of life.