Local Thrombolysis in Acute and Extended Portal Vein and TIPS Thrombosis in a Patient with Decompensated Cirrhosis and Protein S Deficiency

Authors

  • Magdalena Rusu Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
  • Maria Imbuzan Liver Research Club, Cluj- Napoca, Romania
  • Raluca Hategan Department of Anesthesia and Intensive Care, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology Cluj-Napoca, Romania
  • Oana Nicoara-Farcau Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
  • Horia Stefanescu Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
  • Bogdan Procopet Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca; Department of Internal Medicine, Iuliu Hatieganu, University of Medicine and Pharmacy, Cluj-Napoca, Romania

DOI:

https://doi.org/10.15403/jgld-1584

Keywords:

tissue plasminogen activator, splanchnic vein thrombosis, transjugular intrahepatic portosystemic shunt, prothrombotic condition

Abstract

This report describes the use of local thrombolysis using a tissue plasminogen activator in a case of a patient with refractory ascites referred for transjugular intrahepatic portosystemic shunt (TIPS) insertion. After successful TIPS insertion, the patient developed acute extended portal vein and TIPS thrombosis, which were treated with local thrombolysis using a tissue plasminogen activator, followed by the complete resolution of ascites. Although there are only limited published data of local thrombolysis for acute splanchnic vein thrombosis, we also review the relevance of the problem in the context of advanced liver disease.

Downloads

Published

2020-10-27

How to Cite

1.
Rusu M, Imbuzan M, Hategan R, Nicoara-Farcau O, Stefanescu H, Procopet B. Local Thrombolysis in Acute and Extended Portal Vein and TIPS Thrombosis in a Patient with Decompensated Cirrhosis and Protein S Deficiency. JGLD [Internet]. 2020 Oct. 27 [cited 2026 Feb. 10];29(4):677-80. Available from: https://jgld.ro/jgld/index.php/jgld/article/view/1584

Issue

Vol. 29 No. 4: December 2020

Section

Case Reports