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Affiliations
Magdalena Rusu
Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
Maria Imbuzan
Liver Research Club, Cluj- Napoca, Romania
Raluca Hategan
Department of Anesthesia and Intensive Care, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology Cluj-Napoca, Romania
Oana Nicoara-Farcau
Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
Horia Stefanescu
Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca, Romania
Bogdan Procopet
Department of Hepatology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca; Liver Research Club, Cluj- Napoca; Department of Internal Medicine, Iuliu Hatieganu, University of Medicine and Pharmacy, Cluj-Napoca, Romania
How to Cite
Local Thrombolysis in Acute and Extended Portal Vein and TIPS Thrombosis in a Patient with Decompensated Cirrhosis and Protein S Deficiency
Abstract
This report describes the use of local thrombolysis using a tissue plasminogen activator in a case of a patient with refractory ascites referred for transjugular intrahepatic portosystemic shunt (TIPS) insertion. After successful TIPS insertion, the patient developed acute extended portal vein and TIPS thrombosis, which were treated with local thrombolysis using a tissue plasminogen activator, followed by the complete resolution of ascites. Although there are only limited published data of local thrombolysis for acute splanchnic vein thrombosis, we also review the relevance of the problem in the context of advanced liver disease.