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Affiliations
Tadahisa Inoue
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
Hitoshi Sano
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
Takashi Mizushima
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
Hirotada Nishie
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
Hiroyasu Iwasaki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
Fumihiro Okumura
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan
How to Cite
A Case of Duodenal Neuroendocrine Carcinoma Treated with Amrubicin as Second-line Chemotherapy
- Tadahisa Inoue ,
- Hitoshi Sano ,
- Takashi Mizushima ,
- Hirotada Nishie ,
- Hiroyasu Iwasaki ,
- Fumihiro Okumura
Vol 24 No 3: September 2015
Section: Case Reports
Pages: 379-382
Abstract
We present the case of a Japanese man in his 60s with duodenal neuroendocrine carcinoma with distant metastases. Chemotherapy with irinotecan plus cisplatin was initiated as a first-line regimen. However, disease progression was observed after only two cycles. Therefore, amrubicin was administered as a second-line chemotherapy. The patient showed a long-term effect of amrubicin therapy, and the best response was a partial response after seven cycles. For duodenal neuroendocrine carcinoma, amrubicin therapy can be considered an effective treatment option as salvage chemotherapy.